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Patent Description

NEWS 1
Blood-glucose control milk powder for diabetes care passes Phase IIA trials
(BiotechEast staff)14 April, 2004

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Local newspaper The China Times reported today that a new method of blood-glucose control had proven effective in Phase IIA clinical trials in Taiwan.
Called Glucose Tolerance Factor (GT&F), the product is a modified milk power, the invention a result of collaboration between National Chunghsing University and local company Maxluck Biotech Corp.
The coordinator of the research team that invented GT&F, Chunghsing Associate Professor Frank Chinhung Mao, said that the university and Maxluck began cooperation three years ago, with GTF the result of two years intensive research and effort.
The group selected for the clinical trial were type II diabetes mellitus patients. This type of diabetes accounts for 95 percent of all diabetes cases, according to Mao. The two-year, 156-patient trial was conducted at 4 local universities; National Taiwan University Hospital, Taichung Veteran's General Hospital, National Chingkung University Hospital, and Tri-service General Hospital.
Mao stated that after four months of consuming GT&F, trial subjects displayed significant improvements in sensitivity to insulin, which leads to a lowering of blood sugar levels on an empty stomach, with women displaying more obvious improvements. The trial indicated that positive results can be seen within only one or two month's consumption of the milk powder, all without side effects, according to Mao.
Mao said that GT&F, once commercialized, would allow for considerable cost savings for the treatment of diabetes patients.

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NEWS 2
Taiwanese Biotechnology Firm Introduces Possible Solution To Glucose Tolerance Lack Among Type II Diabetics
January 16, 2008 10:31 a.m. EST
Vittorio Hernandez - AHN News Writer

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Manila, Philippines (AHN) - A Taiwanese biotechnology company is bringing into the Philippines a possible solution for the glucose tolerance factor lack among Type II diabetics. Tainan-based Maxluck Biotechnology is launching on Thursday the GT and F milk, which helps human cells absorb glucose.
Dr. Frank Mao Chia Hung of Maxluck Biotechnology Corporation explained contrary to common belief that diabetes is an ailment, it is more the inability of the glucose to enter the cells rather than the failure of the pancreas to produce insulin. Using biotechnology he invented an element called trivalent chromium, which helps the glucose enter the cell and be converted as energy, instead of remaining in the blood and causing high blood sugar among Type II diabetics.
Trivalent chromium mimics the action of colostrum, found in mother's milk. Colostrum has large amounts of antibodies that protects the baby's vital body parts and plays a major role in producing chemical reactions to maintain life, including the conversion of glucose into energy. But since mother's milk is not available except for her newborn, Mao tapped biotechnology to come up with trivalent chromium.
Initially, Maxluck manufactured it as milk powder, but because of complaints by some diabetics of lactose intolerance, the company produced a second generation of trivalent chromium in capsule form.
Aside from helping Type II diabetics reduce their dependence on oral medication which often has side effects, trivalent chromium has been proven to help obese diabetics deal with their weight problems.
The GTF products are expected to be accepted widely by Filipinos, many of whom are prone to diabetes because of genetic predisposition and the Filipino diet that is high in sugar and fat contents. Worldwide, there are 250 million diabetics, expected to double within the next 30 years, Mao said.

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